Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark.

نویسندگان

  • E O Ajaiyeoba
  • P A Onocha
  • S O Nwozo
  • W Sama
چکیده

Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol.

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عنوان ژورنال:
  • Fitoterapia

دوره 74 7-8  شماره 

صفحات  -

تاریخ انتشار 2003